As you may remember, I was recently diagnosed with osteoporosis. I've consulted with my gyn, a nutritionist, and most recently a physical therapist who is teaching me the correct form for both pilates and weightlifting.
I've given up gluten, as suggested by the gyn, and switched to healthy fats and lots more of them as suggested by the nutritionist. Both of these professionals sell supplements, but not the same brand of supplements. They have me on all sorts of things that I was beginning to think my be doing more for them than for me. FYI – in addition to a spoonful of coconut oil per day (which is actually pretty tasty) I take a spoonful of cinnamon-flavored flax seed oil (almost icky).

My first meeting with the physical therapist was truly informative. She looked at the list of pills and my normal diet and said "you aren't getting enough calcium." She's a believer is getting what you need from food first (and I tend to agree with her) but it's hard when you've been told no milk or cheese or Total cereal (one of her favorite calcium-rich foods). So I've added mustard greens, almonds, and Oikos plain non-fat yogurt to my daily diet.
She also recommended CitriCal for my calcium supplement (backed by good research) and Women's One-A-Day vitamins for women over 50. Both of these are cheaper and easier to find than the fancy supplements I was taking. Then she said something about taking my pills 15-20 minutes after a meal. This was in passing, just a quick thought.
I stopped her because I have always taken my pills 'with food' – meaning 'while I was eating.' I could tell from her expression that she thought I was maybe not that bright because, of course, with food means after food. Not to me because I tend to be literal. If they want you to take pills 20 miinutes after eating the instructions should say just that.
This is the what I've learned: When you take pills is important. It's possible that the calcium problems I have are because I've taken my pills at the wrong time for 8 years. If nothing else, it can't have helped.
Those of you who already know when to take your pills, pat yourself on the back and be happy. Those of you who are doing what I was doing, ask you physician exactly when you should be taking your pills. I hope this is helpful to someone because I do wish I had known this sooner.